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Computing power of quantitative trait locus association mapping for haploid loci

BACKGROUND: Statistical power calculations are a critical part of any study design for gene mapping. Most calculations assume that the locus of interest is biallelic. However, there are common situations in human genetics such as X-linked loci in males where the locus is haploid. The purpose of this...

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Detalhes bibliográficos
Main Authors: Gordon, Derek, Zinn, Andrew R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738682/
https://ncbi.nlm.nih.gov/pubmed/19698182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-261
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