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Anterior segment dysgenesis correlation with epithelial-mesenchymal transition in Smad4 knockout mice
AIM: To explore the molecular mechanisms in lens development and the pathogenesis of Peters anomaly in Smad4 defective mice. METHODS: Le-Cre transgenic mouse line was employed to inactivate Smad4 in the surface ectoderm selectively. Pathological techniques were used to reveal the morphological chang...
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| Опубликовано в: : | Int J Ophthalmol |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
International Journal of Ophthalmology Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951671/ https://ncbi.nlm.nih.gov/pubmed/27500098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2016.07.02 |
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