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Anterior segment dysgenesis correlation with epithelial-mesenchymal transition in Smad4 knockout mice

AIM: To explore the molecular mechanisms in lens development and the pathogenesis of Peters anomaly in Smad4 defective mice. METHODS: Le-Cre transgenic mouse line was employed to inactivate Smad4 in the surface ectoderm selectively. Pathological techniques were used to reveal the morphological chang...

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Detalhes bibliográficos
Publicado no:Int J Ophthalmol
Main Authors: Li, Jing, Qin, Yu, Zhao, Fang-Kun, Wu, Di, He, Xue-Fei, Liu, Jia, Zhao, Jiang-Yue, Zhang, Jin-Song
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951671/
https://ncbi.nlm.nih.gov/pubmed/27500098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2016.07.02
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