Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides

Brain delivery of macromolecular therapeutics (e.g., proteins) remains an unsolved problem because of the formidable blood–brain barrier (BBB). Although a direct pathway of nose-to-brain transfer provides an answer to circumventing the BBB and has already been intensively investigated for brain deli...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Lin, Tingting, Liu, Ergang, He, Huining, Shin, Meong Cheol, Moon, Cheol, Yang, Victor C., Huang, Yongzhuo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951590/
https://ncbi.nlm.nih.gov/pubmed/27471676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.04.001
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