An Open-Label Investigation of the Pharmacokinetics and Tolerability of Oral Cysteamine in Adults with Cystic Fibrosis

BACKGROUND AND OBJECTIVE: Cysteamine is licensed for use in nephropathic cystinosis but preclinical data suggest a role in managing cystic fibrosis (CF). This study aimed to determine whether oral cysteamine is absorbed in adult CF patients and enters the bronchial secretions. Tolerability outcomes...

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Bibliografiske detaljer
Udgivet i:Clin Drug Investig
Main Authors: Devereux, Graham, Steele, Sandra, Griffiths, Kairen, Devlin, Edward, Fraser-Pitt, Douglas, Cotton, Seonaidh, Norrie, John, Chrystyn, Henry, O’Neil, Deborah
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951511/
https://ncbi.nlm.nih.gov/pubmed/27153825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-016-0405-z
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