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Cysteamine as a Future Intervention in Cystic Fibrosis Against Current and Emerging Pathogens: A Patient-based ex vivo Study Confirming its Antimicrobial and Mucoactive Potential in Sputum

BACKGROUND: Cysteamine has recently been shown to have in vitro properties potentially therapeutically beneficial in cystic fibrosis (CF). In this study we investigated the antimicrobial and mucolytic activity of cysteamine against the complex biologic matrix of CF sputum. METHODS: Sputum samples we...

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Bibliografiske detaljer
Udgivet i:EBioMedicine
Main Authors: Devereux, Graham, Fraser-Pitt, Douglas, Robertson, Jennifer, Devlin, Edward, Mercer, Derry, O'Neil, Deborah
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634621/
https://ncbi.nlm.nih.gov/pubmed/26629546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.08.018
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