Cysteamine as a Future Intervention in Cystic Fibrosis Against Current and Emerging Pathogens: A Patient-based ex vivo Study Confirming its Antimicrobial and Mucoactive Potential in Sputum

BACKGROUND: Cysteamine has recently been shown to have in vitro properties potentially therapeutically beneficial in cystic fibrosis (CF). In this study we investigated the antimicrobial and mucolytic activity of cysteamine against the complex biologic matrix of CF sputum. METHODS: Sputum samples we...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Devereux, Graham, Fraser-Pitt, Douglas, Robertson, Jennifer, Devlin, Edward, Mercer, Derry, O'Neil, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634621/
https://ncbi.nlm.nih.gov/pubmed/26629546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.08.018
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