Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer

HER2-positive advanced gastric cancer patients frequently develop resistance to trastuzumab through mechanisms still poorly understood. In breast cancer, other members of the HER-family are known to be involved in trastuzumab-resistance, as is overexpression of the scaffold protein IQGAP1. In the pr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Arienti, Chiara, Zanoni, Michele, Pignatta, Sara, Del Rio, Alberto, Carloni, Silvia, Tebaldi, Michela, Tedaldi, Gianluca, Tesei, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951299/
https://ncbi.nlm.nih.gov/pubmed/26919099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7575
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