β(2)-Adrenogenic signaling regulates NNK-induced pancreatic cancer progression via upregulation of HIF-1α

Cigarette smoking is a risk factor for pancreatic cancer. It is suggested that 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific nitrosamine, mediates the carcinogenic action of cigarette smoking by promoting cancer growth. In the present study, we show that smoking, HIF-1α ex...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Zhang, Dong, Lei, Jianjun, Ma, Jiguang, Chen, Xin, Sheng, Liang, Jiang, Zhengdong, Nan, Ligang, Xu, Qinhong, Duan, Wanxing, Wang, Zheng, Li, Xuqi, Wu, Zheng, Wu, Erxi, Ma, Qingyong, Huo, Xiongwei
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951248/
https://ncbi.nlm.nih.gov/pubmed/26497365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.5677
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