Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway

Metastasis is the major cause for the high mortality rate of pancreatic cancer. Human embryonic stem cell (hESC) associated genes frequently correlate with malignant disease progression. Recent studies have demonstrated that the embryonic protein Nodal, which plays a critical role during embryonic d...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Duan, Wanxing, Li, Rong, Ma, Jiguang, Lei, Jianjun, Xu, Qinhong, Jiang, Zhengdong, Nan, Ligang, Li, Xuqi, Wang, Zheng, Huo, Xiongwei, Han, Liang, Wu, Zheng, Wu, Erxi, Ma, Qingyong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359309/
https://ncbi.nlm.nih.gov/pubmed/25557170
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