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Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway

Metastasis is the major cause for the high mortality rate of pancreatic cancer. Human embryonic stem cell (hESC) associated genes frequently correlate with malignant disease progression. Recent studies have demonstrated that the embryonic protein Nodal, which plays a critical role during embryonic d...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Duan, Wanxing, Li, Rong, Ma, Jiguang, Lei, Jianjun, Xu, Qinhong, Jiang, Zhengdong, Nan, Ligang, Li, Xuqi, Wang, Zheng, Huo, Xiongwei, Han, Liang, Wu, Zheng, Wu, Erxi, Ma, Qingyong
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359309/
https://ncbi.nlm.nih.gov/pubmed/25557170
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