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Deficiency in Cardiolipin Reduces Doxorubicin-Induced Oxidative Stress and Mitochondrial Damage in Human B-Lymphocytes

Cardiolipin (CL) is an inner mitochondrial membrane phospholipid which plays an important role in mitochondrial function. Perturbation in CL biosynthesis alters mitochondrial bioenergetics causing a severe genetic disorder commonly known as Barth syndrome. Barth syndrome patients are known to have a...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Aryal, Baikuntha, Rao, V. Ashutosh
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951097/
https://ncbi.nlm.nih.gov/pubmed/27434059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158376
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