Molecular mechanisms autonomic dysfunction and impaired cardiac contractility in critical illness

Objectives: Molecular mechanisms linking autonomic dysfunction with poorer clinical outcomes in critical illness remain unclear. We hypothesized that baroreflex dysfunction alone is sufficient to cause cardiac impairment through neurohormonal activation of (NADPH oxidase-dependent) oxidative stress...

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Publicat a:Crit Care Med
Autors principals: Ackland, Gareth L., Whittle, John, Toner, Andrew, Machhada, Asif, Gutierrez Del Arroyo, Ana, Sciuso, Alberto, Jenkins, Nicholas, Dyson, Alex, Struthers, Richard, Sneyd, Robert, Minto, Gary, Singer, Mervyn, Shah, Ajay M., Gourine, Alexander V.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950969/
https://ncbi.nlm.nih.gov/pubmed/26950003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000001606
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