Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing

Mammalian pre-implantation development is a complex process involving dramatic changes in the transcriptional architecture(1–4). We report here a comprehensive analysis of transcriptome dynamics from oocyte to morula in both human and mouse embryos, using single-cell RNA sequencing. Based on single-...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Xue, Zhigang, Huang, Kevin, Cai, Chaochao, Cai, Lingbo, Jiang, Chun-yan, Feng, Yun, Liu, Zhenshan, Zeng, Qiao, Cheng, Liming, Sun, Yi E., Liu, Jia-yin, Horvath, Steve, Fan, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950944/
https://ncbi.nlm.nih.gov/pubmed/23892778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12364
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