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Ribosome RNA Assembly Intermediates Visualized in Living Cells

In cells, RNAs likely adopt numerous intermediate conformations prior to formation of functional RNA-protein complexes. We used single-nucleotide resolution SHAPE to probe the structure of E. coli 16S ribosomal RNA (rRNA) in healthy growing bacteria. SHAPE-directed modeling indicated that the predom...

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Publicat a:Biochemistry
Autors principals: McGinnis, Jennifer L., Weeks, Kevin M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950920/
https://ncbi.nlm.nih.gov/pubmed/24818530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500198b
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