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In-cell SHAPE reveals that free 30S ribosome subunits are in the inactive state

It was shown decades ago that purified 30S ribosome subunits readily interconvert between “active” and “inactive” conformations in a switch that involves changes in the functionally important neck and decoding regions. However, the physiological significance of this conformational change had remaine...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: McGinnis, Jennifer L., Liu, Qi, Lavender, Christopher A., Devaraj, Aishwarya, McClory, Sean P., Fredrick, Kurt, Weeks, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345610/
https://ncbi.nlm.nih.gov/pubmed/25675474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411514112
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