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Role of endothelial TRPV4 channels in vascular actions of the endocannabinoid, 2‐arachidonoylglycerol

BACKGROUND AND PURPOSE: Metabolites of the endocannabinoid, 2‐arachidonoylglycerol (2‐AG) have been postulated to act as endogenous activators of TRPV4, a Ca(2+)‐permeable cation channel that plays a critical role in endothelium‐dependent relaxation. However, it is unclear if TRPV4 contributes to th...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Ho, W S V, Zheng, X, Zhang, D X
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950792/
https://ncbi.nlm.nih.gov/pubmed/26294342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13312
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