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Modified Nucleotides for Discrimination between Cytosine and the Epigenetic Marker 5‐Methylcytosine
5‐Methyl‐2′‐deoxycytosine, the most common epigenetic marker of DNA in eukaryotic cells, plays a key role in gene regulation and affects various cellular processes such as development and carcinogenesis. Therefore, the detection of 5mC can serve as an important biomarker for diagnostics. Here we des...
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| Publicado en: | Angew Chem Int Ed Engl |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4949677/ https://ncbi.nlm.nih.gov/pubmed/26835661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511520 |
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