Subtle Structural Differences Trigger Inhibitory Activity of Propafenone Analogues at the Two Polyspecific ABC Transporters: P‐Glycoprotein (P‐gp) and Breast Cancer Resistance Protein (BCRP)

The transmembrane ABC transporters P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) are widely recognized for their role in cancer multidrug resistance and absorption and distribution of compounds. Furthermore, they are linked to drug–drug interactions and toxicity. Nevertheless, du...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Schwarz, Theresa, Montanari, Floriane, Cseke, Anna, Wlcek, Katrin, Visvader, Lene, Palme, Sarah, Chiba, Peter, Kuchler, Karl, Urban, Ernst, Ecker, Gerhard F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949556/
https://ncbi.nlm.nih.gov/pubmed/26970257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500592
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados