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Virtual Screening of DrugBank Reveals Two Drugs as New BCRP Inhibitors

The breast cancer resistance protein (BCRP) is an ABC transporter playing a crucial role in the pharmacokinetics of drugs. The early identification of substrates and inhibitors of this efflux transporter can help to prevent or foresee drug-drug interactions. In this work, we built a ligand-based in...

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Detalles Bibliográficos
Publicado en:J Biomol Screen
Autores principales: Montanari, Floriane, Cseke, Anna, Wlcek, Katrin, Ecker, Gerhard F.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302078/
https://ncbi.nlm.nih.gov/pubmed/27401583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116657513
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