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Alkylation of Staurosporine to Derive a Kinase Probe for Fluorescence Applications
The natural product staurosporine is a high‐affinity inhibitor of nearly all mammalian protein kinases. The labelling of staurosporine has proven effective as a means of generating protein kinase research tools. Most tools have been generated by acylation of the 4′‐methylamine of the sugar moiety of...
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| Udgivet i: | ChemMedChem |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4949516/ https://ncbi.nlm.nih.gov/pubmed/27008372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500589 |
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