Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection

BACKGROUND: Chronic hepatitis C virus (HCV) infection of the liver with either genotype 1 or genotype 3 gives rise to distinct pathologies, and the two viral genotypes respond differently to antiviral therapy. METHODS: To understand these clinical differences, we compared gene transcription profiles...

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Bibliografiske detaljer
Udgivet i:Liver Int
Main Authors: Robinson, Mark W., Aranday‐Cortes, Elihu, Gatherer, Derek, Swann, Rachael, Liefhebber, Jolanda M. P., Filipe, Ana Da Silva, Sigruener, Alex, Barclay, Stephen T., Mills, Peter R., Patel, Arvind H., McLauchlan, John
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Viral Hepatitis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949513/
https://ncbi.nlm.nih.gov/pubmed/25800823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12830
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