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MINDEC-An Enhanced Negative Depletion Strategy for Circulating Tumour Cell Enrichment

Most current methods of circulating tumour cell (CTC) enrichment target the epithelial protein EpCAM, which is commonly expressed in adenocarcinoma cells. However, such methods will not recover the fraction of CTCs that have a non-epithelial phenotype due to epithelial–mesenchymal transition. For ph...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lapin, Morten, Tjensvoll, Kjersti, Oltedal, Satu, Buhl, Tove, Gilje, Bjørnar, Smaaland, Rune, Nordgård, Oddmund
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949475/
https://ncbi.nlm.nih.gov/pubmed/27432216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28929
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