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MINDEC-An Enhanced Negative Depletion Strategy for Circulating Tumour Cell Enrichment

Most current methods of circulating tumour cell (CTC) enrichment target the epithelial protein EpCAM, which is commonly expressed in adenocarcinoma cells. However, such methods will not recover the fraction of CTCs that have a non-epithelial phenotype due to epithelial–mesenchymal transition. For ph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Lapin, Morten, Tjensvoll, Kjersti, Oltedal, Satu, Buhl, Tove, Gilje, Bjørnar, Smaaland, Rune, Nordgård, Oddmund
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949475/
https://ncbi.nlm.nih.gov/pubmed/27432216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28929
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