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MINDEC-An Enhanced Negative Depletion Strategy for Circulating Tumour Cell Enrichment

Most current methods of circulating tumour cell (CTC) enrichment target the epithelial protein EpCAM, which is commonly expressed in adenocarcinoma cells. However, such methods will not recover the fraction of CTCs that have a non-epithelial phenotype due to epithelial–mesenchymal transition. For ph...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lapin, Morten, Tjensvoll, Kjersti, Oltedal, Satu, Buhl, Tove, Gilje, Bjørnar, Smaaland, Rune, Nordgård, Oddmund
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949475/
https://ncbi.nlm.nih.gov/pubmed/27432216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28929
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