Cortactin promotes exosome secretion by controlling branched actin dynamics

Exosomes are extracellular vesicles that influence cellular behavior and enhance cancer aggressiveness by carrying bioactive molecules. The mechanisms that regulate exosome secretion are poorly understood. Here, we show that the actin cytoskeletal regulatory protein cortactin promotes exosome secret...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Sinha, Seema, Hoshino, Daisuke, Hong, Nan Hyung, Kirkbride, Kellye C., Grega-Larson, Nathan E., Seiki, Motoharu, Tyska, Matthew J., Weaver, Alissa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2016
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949450/
https://ncbi.nlm.nih.gov/pubmed/27402952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201601025
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