Cortactin promotes exosome secretion by controlling branched actin dynamics

Exosomes are extracellular vesicles that influence cellular behavior and enhance cancer aggressiveness by carrying bioactive molecules. The mechanisms that regulate exosome secretion are poorly understood. Here, we show that the actin cytoskeletal regulatory protein cortactin promotes exosome secret...

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Foilsithe in:J Cell Biol
Main Authors: Sinha, Seema, Hoshino, Daisuke, Hong, Nan Hyung, Kirkbride, Kellye C., Grega-Larson, Nathan E., Seiki, Motoharu, Tyska, Matthew J., Weaver, Alissa M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2016
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949450/
https://ncbi.nlm.nih.gov/pubmed/27402952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201601025
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