Cortactin promotes exosome secretion by controlling branched actin dynamics

Exosomes are extracellular vesicles that influence cellular behavior and enhance cancer aggressiveness by carrying bioactive molecules. The mechanisms that regulate exosome secretion are poorly understood. Here, we show that the actin cytoskeletal regulatory protein cortactin promotes exosome secret...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Sinha, Seema, Hoshino, Daisuke, Hong, Nan Hyung, Kirkbride, Kellye C., Grega-Larson, Nathan E., Seiki, Motoharu, Tyska, Matthew J., Weaver, Alissa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949450/
https://ncbi.nlm.nih.gov/pubmed/27402952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201601025
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