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Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs

Amyloid-β peptides, through highly sophisticated enzymatic machinery, are universally produced and released in an action potential synchronized manner into the interstitial fluids in the brain. Yet no native functions are attributed to amyloid-β. The amyloid-β hypothesis ascribes just neurotoxicity...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Kumar, Rajnish, Nordberg, Agneta, Darreh-Shori, Taher
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949388/
https://ncbi.nlm.nih.gov/pubmed/26525916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv318
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