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Plasma levels of receptor interacting protein kinase-3 (RIP3), an essential mediator of necroptosis, are associated with acute kidney injury in critically ill trauma patients

BACKGROUND: Receptor interacting protein kinase-3 (RIP3) is a key mediator of necroptosis, a form of regulated cell death recently implicated in murine models of renal ischemia-reperfusion injury and transfusion-associated endothelial injury. The importance of necroptosis in human AKI is unknown. We...

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Vydáno v:Shock
Hlavní autoři: Shashaty, Michael G. S., Reilly, John P., Sims, Carrie A., Holena, Daniel N., Qing, Danielle, Forker, Caitlin M., Hotz, Meghan J., Meyer, Nuala J., Lanken, Paul N., Feldman, Harold I., Christie, Jason D., Mangalmurti, Nilam S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949076/
https://ncbi.nlm.nih.gov/pubmed/26925809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000596
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