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Omeprazole Inhibits Pancreatic Cancer Cell Invasion Through a Non-genomic Aryl Hydrocarbon Receptor Pathway

Omeprazole and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are aryl hydrocarbon receptor (AhR) agonist that inhibit invasion of breast cancer cell through inhibition of CXCR4 transcription. Treatment of highly invasive Panc1 pancreatic cancer cells with TCDD, omeprazole and seven other AhR-active pha...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Jin, Un-Ho, Kim, Sang-Bae, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948974/
https://ncbi.nlm.nih.gov/pubmed/25826687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx5005198
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