Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors

We identified phosphatidylinositol glycan anchor biosynthesis, class X (PIGX), which plays a critical role in the biosynthetic pathway of glycosylphosphatidylinositol (GPI)-anchor motif, to be upregulated highly and frequently in breast cancer cells. Knockdown of PIGX as well as reticulocalbin 1 (RC...

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Foilsithe in:Int J Oncol
Main Authors: Nakakido, Makoto, Tamura, Kenji, Chung, Suyoun, Ueda, Koji, Fujii, Risa, Kiyotani, Kazuma, Nakamura, Yusuke
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2016
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948962/
https://ncbi.nlm.nih.gov/pubmed/27572108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3607
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