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Inhibition of Advanced Glycation End Products (AGEs) Accumulation by Pyridoxamine Modulates Glomerular and Mesangial Cell Estrogen Receptor α Expression in Aged Female Mice
Age-related increases in oxidant stress (OS) play a role in regulation of estrogen receptor (ER) expression in the kidneys. In this study, we establish that in vivo 17β-estradiol (E(2)) replacement can no longer upregulate glomerular ER expression by 21 months of age in female mice (anestrous). We h...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4948910/ https://ncbi.nlm.nih.gov/pubmed/27428057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159666 |
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