HIV-1 Subtype C Mosaic Gag Expressed by BCG and MVA Elicits Persistent Effector T Cell Responses in a Prime-Boost Regimen in Mice

Over 90% of HIV/AIDS positive individuals in sub-Saharan Africa are infected with highly heterogeneous HIV-1 subtype C (HIV-1C) viruses. One of the best ways to reduce the burden of this disease is the development of an affordable and effective prophylactic vaccine. Mosaic immunogens are computation...

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Publicado en:PLoS One
Autores principales: Jongwe, Tsungai Ivai, Chapman, Ros, Douglass, Nicola, Chetty, Shivan, Chege, Gerald, Williamson, Anna-Lise
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948879/
https://ncbi.nlm.nih.gov/pubmed/27427967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159141
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