Priming with a Recombinant Pantothenate Auxotroph of Mycobacterium bovis BCG and Boosting with MVA Elicits HIV-1 Gag Specific CD8(+) T Cells

A safe and effective HIV vaccine is required to significantly reduce the number of people becoming infected with HIV each year. In this study wild type Mycobacterium bovis BCG Pasteur and an attenuated pantothenate auxotroph strain (BCGΔpanCD) that is safe in SCID mice, have been compared as vaccine...

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Detalhes bibliográficos
Main Authors: Chapman, Rosamund, Shephard, Enid, Stutz, Helen, Douglass, Nicola, Sambandamurthy, Vasan, Garcia, Irene, Ryffel, Bernhard, Jacobs, William, Williamson, Anna-Lise
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315557/
https://ncbi.nlm.nih.gov/pubmed/22479338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032769
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