Priming with a Recombinant Pantothenate Auxotroph of Mycobacterium bovis BCG and Boosting with MVA Elicits HIV-1 Gag Specific CD8(+) T Cells

A safe and effective HIV vaccine is required to significantly reduce the number of people becoming infected with HIV each year. In this study wild type Mycobacterium bovis BCG Pasteur and an attenuated pantothenate auxotroph strain (BCGΔpanCD) that is safe in SCID mice, have been compared as vaccine...

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Hlavní autoři: Chapman, Rosamund, Shephard, Enid, Stutz, Helen, Douglass, Nicola, Sambandamurthy, Vasan, Garcia, Irene, Ryffel, Bernhard, Jacobs, William, Williamson, Anna-Lise
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315557/
https://ncbi.nlm.nih.gov/pubmed/22479338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032769
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