Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice

Statins, which are revolutionized cholesterol-lowing agents, have been reported to have unfavorable effects on the liver. Inflammatory stress is a susceptibility factor for drug-induced liver injury. This study investigated whether inflammatory stress sensitized the liver to statin-induced toxicity...

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Publicat a:PLoS One
Autors principals: Wu, Wei, Zhao, Lei, Yang, Ping, Zhou, Wei, Li, Beibei, Moorhead, John F., Varghese, Zac, Ruan, Xiong Z., Chen, Yaxi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948878/
https://ncbi.nlm.nih.gov/pubmed/27428373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159512
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