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Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo
Insulin resistance is closely related to inflammatory stress and the mammalian target of rapamycin/S6 kinase (mTOR/S6K) pathway. The present study investigated whether rapamycin, a specific inhibitor of mTOR, ameliorates inflammatory stress-induced insulin resistance in vitro and in vivo. We used tu...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598825/ https://ncbi.nlm.nih.gov/pubmed/26449763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14959 |
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