Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacological modulation

Acute myeloid leukemia (AML) is characterized by the accumulation of immature blood cell precursors in the bone marrow. Pharmacologically overcoming the differentiation block in this condition is an attractive therapeutic avenue, which has only achieved success in a subtype of AML, acute promyelocyt...

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Publicado no:Exp Hematol
Main Authors: Orfali, Nina, O’Donovan, Tracey R., Nyhan, Michelle J., Britschgi, Adrian, Tschan, Mario P., Cahill, Mary R., Mongan, Nigel P., Gudas, Lorraine J., McKenna, Sharon L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948855/
https://ncbi.nlm.nih.gov/pubmed/25986473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.04.012
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