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Serum Amyloid P Component Ameliorates Neurological Damage Caused by Expressing a Lysozyme Variant in the Central Nervous System of Drosophila melanogaster

Lysozyme amyloidosis is a hereditary disease in which mutations in the gene coding for lysozyme leads to misfolding and consequently accumulation of amyloid material. To improve understanding of the processes involved we expressed human wild type (WT) lysozyme and the disease-associated variant F57I...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Helmfors, Linda, Bergkvist, Liza, Brorsson, Ann-Christin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948765/
https://ncbi.nlm.nih.gov/pubmed/27428539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159294
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