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Nanoparticle tumor localization, disruption of autophagosomal trafficking, and prolonged drug delivery improve survival in peritoneal mesothelioma

The treatment outcomes for malignant peritoneal mesothelioma are poor and associated with high co-morbidities due to suboptimal drug delivery. Thus, there is an unmet need for new approaches that concentrate drug at the tumor for a prolonged period of time yielding enhanced antitumor efficacy and im...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Liu, Rong, Colby, Aaron H., Gilmore, Denis, Schulz, Morgan, Zeng, Jialiu, Padera, Robert F., Shirihai, Orian, Grinstaff, Mark W., Colson, Yolonda L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948582/
https://ncbi.nlm.nih.gov/pubmed/27343465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.06.031
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