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In Vitro Activity of Paclitaxel-Loaded Polymeric Expansile Nanoparticles in Breast Cancer Cells

Through a series of in vitro studies, the essential steps for intracellular drug delivery of paclitaxel using a pH-responsive nanoparticle system have been investigated in breast cancer cells. We successfully encapsulated paclitaxel within polymeric expansile nanoparticles (Pax-eNPs) at 5% loading v...

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Detalhes bibliográficos
Main Authors: Zubris, Kimberly Ann V., Liu, Rong, Colby, Aaron, Schulz, Morgan D., Colson, Yolonda L., Grinstaff, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915286/
https://ncbi.nlm.nih.gov/pubmed/23617223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm400434h
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