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Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency

Despite research efforts, cell uptake processes determining siRNA silencing efficiency remain unclear. Here, we examine the relationship between in vitro cell culture models, cellular trafficking and siRNA silencing efficiency to provide a mechanistic insight on siRNA delivery system design. Model s...

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Detalles Bibliográficos
Publicado en:Biochem Biophys Res Commun
Main Authors: Capel, Victoria, Vllasaliu, Driton, Watts, Peter, Stolnik, Snow
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948577/
https://ncbi.nlm.nih.gov/pubmed/27349867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.06.054
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