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Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency

Despite research efforts, cell uptake processes determining siRNA silencing efficiency remain unclear. Here, we examine the relationship between in vitro cell culture models, cellular trafficking and siRNA silencing efficiency to provide a mechanistic insight on siRNA delivery system design. Model s...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Capel, Victoria, Vllasaliu, Driton, Watts, Peter, Stolnik, Snow
Format: Artigo
Language:Inglês
Published: Elsevier 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948577/
https://ncbi.nlm.nih.gov/pubmed/27349867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.06.054
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