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Biomechanics of red blood cells in human spleen and consequences for physiology and disease

Red blood cells (RBCs) can be cleared from circulation when alterations in their size, shape, and deformability are detected. This function is modulated by the spleen-specific structure of the interendothelial slit (IES). Here, we present a unique physiological framework for development of prognosti...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Pivkin, Igor V., Peng, Zhangli, Karniadakis, George E., Buffet, Pierre A., Dao, Ming, Suresh, Subra
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948333/
https://ncbi.nlm.nih.gov/pubmed/27354532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606751113
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