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Biomechanics of red blood cells in human spleen and consequences for physiology and disease

Red blood cells (RBCs) can be cleared from circulation when alterations in their size, shape, and deformability are detected. This function is modulated by the spleen-specific structure of the interendothelial slit (IES). Here, we present a unique physiological framework for development of prognosti...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Pivkin, Igor V., Peng, Zhangli, Karniadakis, George E., Buffet, Pierre A., Dao, Ming, Suresh, Subra
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948333/
https://ncbi.nlm.nih.gov/pubmed/27354532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606751113
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