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Advantages of using the QIAshredder instead of restriction digestion to prepare DNA for droplet digital PCR

The viscosity of genomic DNA can interfere with digital PCR systems that partition samples into oil droplets or microfluidic wells. Restriction digestion may reduce the viscosity, but the process is labor-intensive, and the buffer can alter the conditions for PCR. DNA fragmentation using the QIAshre...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Biotechniques
Asıl Yazarlar: Yukl, Steven A., Kaiser, Philipp, Kim, Peggy, Li, Peilin, Wong, Joseph K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948299/
https://ncbi.nlm.nih.gov/pubmed/24724845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/000114159
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