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Attenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate

BACKGROUND: Methotrexate (MTX), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive sys- tem in mice. The aim of this research was to study the effects of ethyl pyruvate (EP) on embryo development and oxidative stress...

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Publicado en:Int J Fertil Steril
Autores principales: Najafi, Gholamreza, Atashfaraz, Elham, Farokhi, Farah
Formato: Artigo
Lenguaje:Inglês
Publicado: Royan Institute 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948076/
https://ncbi.nlm.nih.gov/pubmed/27441057
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