Silibinin attenuates methotrexate-induced pulmonary injury by targeting oxidative stress

The aim of the present study was to assess the protective effect of silibinin against methotrexate (MTX)-induced pulmonary toxicity. Rats were divided into four groups (MTX, MTX + silibinin, silibinin and control. MTX was injected intraperitoneally (i.p) into female Wistar rats (10 mg/kg/day for 3 d...

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Published in:Exp Ther Med
Main Authors: KALEMCI, SERDAR, TOPAL, YASAR, CELIK, SERKAN YASAR, YILMAZ, NIGAR, BEYDILLI, HALIL, KOSAR, MEHMET ILKAY, DIRICAN, NIGAR, ALTUNTAS, IRFAN
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509095/
https://ncbi.nlm.nih.gov/pubmed/26622344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2542
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