Effect of Antifibrotic MicroRNAs Crosstalk on the Action of N-acetyl-seryl-aspartyl-lysyl-proline in Diabetes-related Kidney Fibrosis

N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP) is an endogenous antifibrotic peptide. We found that suppression of AcSDKP and induction of dipeptidyl peptidase-4 (DPP-4), which is associated with insufficient levels of antifibrotic microRNA (miR)s in kidneys, were imperative to understand the mechan...

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Publicat a:Sci Rep
Autors principals: Srivastava, Swayam Prakash, Shi, Sen, Kanasaki, Megumi, Nagai, Takako, Kitada, Munehiro, He, Jianhua, Nakamura, Yuka, Ishigaki, Yasuhito, Kanasaki, Keizo, Koya, Daisuke
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947922/
https://ncbi.nlm.nih.gov/pubmed/27425816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29884
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