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Spatial Moran models, II: cancer initiation in spatially structured tissue
We study the accumulation and spread of advantageous mutations in a spatial stochastic model of cancer initiation on a lattice. The parameters of this general model can be tuned to study a variety of cancer types and genetic progression pathways. This investigation contributes to an understanding of...
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| Publicado no: | J Math Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947874/ https://ncbi.nlm.nih.gov/pubmed/26126947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00285-015-0912-1 |
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