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Detection of atherosclerotic plaques in Apo-E-deficient mice using (99m)Tc-duramycin
Apoptosis of macrophages and smooth muscle cells is linked to atherosclerotic plaque destabilization. The apoptotic cascade leads to exposure of negatively charged phosphatidylethanolamine (PE) on the outer leaflet of the cell membrane, thereby making apoptosis detectable using probes targeting PE....
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| Publicat a: | Nucl Med Biol |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947567/ https://ncbi.nlm.nih.gov/pubmed/27236285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2016.05.007 |
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