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Detection of atherosclerotic plaques in Apo-E-deficient mice using (99m)Tc-duramycin
Apoptosis of macrophages and smooth muscle cells is linked to atherosclerotic plaque destabilization. The apoptotic cascade leads to exposure of negatively charged phosphatidylethanolamine (PE) on the outer leaflet of the cell membrane, thereby making apoptosis detectable using probes targeting PE....
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| 發表在: | Nucl Med Biol |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947567/ https://ncbi.nlm.nih.gov/pubmed/27236285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2016.05.007 |
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