Detection of atherosclerotic plaques in Apo-E-deficient mice using (99m)Tc-duramycin

Apoptosis of macrophages and smooth muscle cells is linked to atherosclerotic plaque destabilization. The apoptotic cascade leads to exposure of negatively charged phosphatidylethanolamine (PE) on the outer leaflet of the cell membrane, thereby making apoptosis detectable using probes targeting PE....

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Udgivet i:Nucl Med Biol
Main Authors: Liu, Zhonglin, Larsen, Brandon T., Lerman, Lilach O., Gray, Brian D., Barber, Christy, Hedayat, Ahmad F., Zhao, Ming, Furenlid, Lars R., Pak, Koon Y., Woolfenden, James M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947567/
https://ncbi.nlm.nih.gov/pubmed/27236285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2016.05.007
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