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Detection of atherosclerotic plaques in Apo-E-deficient mice using (99m)Tc-duramycin

Apoptosis of macrophages and smooth muscle cells is linked to atherosclerotic plaque destabilization. The apoptotic cascade leads to exposure of negatively charged phosphatidylethanolamine (PE) on the outer leaflet of the cell membrane, thereby making apoptosis detectable using probes targeting PE....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucl Med Biol
Prif Awduron: Liu, Zhonglin, Larsen, Brandon T., Lerman, Lilach O., Gray, Brian D., Barber, Christy, Hedayat, Ahmad F., Zhao, Ming, Furenlid, Lars R., Pak, Koon Y., Woolfenden, James M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947567/
https://ncbi.nlm.nih.gov/pubmed/27236285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2016.05.007
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