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Estradiol rapidly attenuates ORL-1 receptor-mediated inhibition of proopiomelanocortin neurons via G(q)-coupled, membrane-initiated signaling
Estradiol rapidly regulates the activity of arcuate nucleus (ARH) proopiomelanocortin (POMC) neurons that project to the medial preoptic nucleus (MPN) to regulate lordosis. Orphanin FQ/nociceptin (OFQ/N) acts via opioid receptor-like (ORL)-1 receptors to inhibit these POMC neurons. Therefore, we tes...
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| Publicado no: | Neuroendocrinology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947458/ https://ncbi.nlm.nih.gov/pubmed/26765570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000443765 |
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