Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci

To determine the effects of single nucleotide polymorphisms (SNPs) identified in a genome-wide association study of progressive supranuclear palsy (PSP), we tested their association with brain gene expression, CpG methylation and neuropathology. In 175 autopsied PSP subjects, we performed associatio...

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Publicado en:Acta Neuropathol
Main Authors: Allen, Mariet, Burgess, Jeremy D., Ballard, Travis, Serie, Daniel, Wang, Xue, Younkin, Curtis S., Sun, Zhifu, Kouri, Naomi, Baheti, Saurabh, Wang, Chen, Carrasquillo, Minerva M., Nguyen, Thuy, Lincoln, Sarah, Malphrus, Kimberly, Murray, Melissa, Golde, Todd, Price, Nathan D., Younkin, Steven G., Schellenberg, Gerard D., Asmann, Yan, Ordog, Tamas, Crook, Julia, Dickson, Dennis, Ertekin-Taner, Nilüfer
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947429/
https://ncbi.nlm.nih.gov/pubmed/27115769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1576-7
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